Comprehensive Antibody Functional Analysis
Experience unparalleled insights into antibody functionality with our cutting-edge suite of analysis tools, customized to your panel requirements
Assessing the performance and potential of your antibodies
Our team recognizes the critical importance of comprehensive antibody functional characterization for successful therapeutic development. We provide thorough evaluations of your antibodies, assessing the binding affinity characteristics to both soluble and membrane-bound targets. Furthermore, we investigate their mechanism of action and effector functions.
Each assay we perform is customized to your unique project requirements, enabling the selection of the best performing antibodies. With our services, you gain the confidence to move forward in your development process, assured in the knowledge that your chosen antibodies have been thoroughly validated and characterized.
SPR
We incorporate Surface Plasmon Resonance (SPR) into our comprehensive antibody characterization. SPR offers real-time, label-free assessment of in vitro protein-protein interactions, allowing us to characterize and rank your antibody panel based on their binding to antigens. Our SPR capabilities extend to include affinity screening, epitope characterization, determination of specificity, mechanism of action investigations, and Fc receptor-binding studies. These detailed insights significantly aid in understanding an antibody potential functionality.
Cell-based Assays
At the core of our bioanalytical capabilities lies our proficiency in cell-based assays, essential for our tailored, advanced antibody characterization services. Our expert cell biologists utilizecutting-edge technology to optimize assay development, delivering key insights into antibody functions. We conduct an extensive range of in vitro functional assays, including binding specificity, cell killing, proliferation studies, antigen-mediated antibody internalization, neutralization, and Fc-mediated effector functions such as ADCP, ADCC, and CDC. These comprehensive assessments probe into antibody activity, efficacy, toxicity, and their mechanism of action, serving as a vital resource throughout the entire biologic development process, from initial discovery to IND submission.