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Yeast Display

Yeast Display Library | High-Affinity Antibody Discovery

Expanding Antibody Discovery

Our advanced platforms, now including Yeast Display, maximize binder diversity and affinity, accelerating the discovery of high-quality antibodies for therapeutic development.

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Yeast Display for Antibody Discovery

Our Yeast Display technology enhances antibody discovery by enabling the identification of high-affinity binders with exceptional precision. Complementing our well-established phage libraries and antibody optimization platforms, it maximizes both binder diversity and affinity, accelerating the path to potent therapeutic candidates. This advanced approach ensures a more comprehensive discovery process, delivering optimized antibodies with superior characteristics.

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Yeast Display Library

Our Yeast Display platform streamlines antibody discovery by combining the power of phage display with high-throughput yeast screening. Starting with our well-established phage libraries, we enrich and clone diverse antibody candidates into yeast display vectors, enabling the direct screening of millions of variants. This approach ensures the selection of high-affinity binders with optimized characteristics for therapeutic development.

Our Yeast Display antibody discovery process includes:

Phage Panning

Utilizing our SuperHuman™, Cosmic™, or Tungsten™ VHH libraries to generate a highly diverse pool of candidates suitable for yeast display screening.

Yeast Display Enrichment

Cloning the selected output into yeast display vectors and isolating high-affinity binders through FACS screening.

Single-Cell Sorting & Analysis

Identifying unique clones with confirmed antigen binding through precise yeast cell sorting and characterization.

High-Throughput Characterization

Streamlining candidate selection without the need for reformatting or cloning, offering flow cytometry-based binding validation, affinity ranking, and kinetics analysis.

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