AnyFormat Manufacturing

AnyFormat Manufacturing

Making Your Protein Fair Game

Great biology only moves forward when the protein is in your hands. AnyFormat Manufacturing delivers any antibody format — IgG, bispecific, multispecific, VHH, ADC intermediate, antigen — at any scale from microgram screening batches to >200 L GLP manufacturing, with the on-time delivery and biophysical quality your programme requires.

Discuss Your Production Requirements

Making Your Protein Fair Game

Great biology only moves forward when the protein is in your hands. AnyFormat Manufacturing delivers any antibody format — IgG, bispecific, multispecific, VHH, ADC intermediate, antigen — at any scale from microgram screening batches to >200 L GLP manufacturing, with the on-time delivery and biophysical quality your programme requires.

Discuss Your Production Requirements

Making Your Protein Fair Game

Great biology only moves forward when the protein is in your hands. AnyFormat Manufacturing delivers any antibody format — IgG, bispecific, multispecific, VHH, ADC intermediate, antigen — at any scale from microgram screening batches to >200 L GLP manufacturing, with the on-time delivery and biophysical quality your programme requires.

Discuss Your Production Requirements

>1,500

multispecific antibodies successfully produced

>90%

success rate for multispecific formats

98%

of projects delivered on time

42%

of projects delivered ahead of schedule

What makes AnyFormat Manufacturing different  

The Ideal Scale for the Data You Need

From 24-well plate screening at microgram scale to >200 L GLP manufacturing, AnyFormat Manufacturing is configured to provide the right amount of the right material at every stage of your programme.

The Format That Fits Your Project

More than 75 different antibody formats produced. More than 900 antibody backbones available in-house. Designed to routinely deliver complex, challenging formats — bispecifics, multispecifics, and beyond.

Quality and Reliable Data

Every batch comes with quality-controlled, reliable data to ensure evidence-based decision-making. 98% on-time delivery across all production scales.

AnyFormat Manufacturing supports programmes from target validation through to development candidate selection — delivering antigen for immunisation campaigns, IgG for characterisation panels, and GMP-grade material for IND-enabling studies.

Value chain positioning

Explore discovery-to-IND

Explore discovery-to-IND

Any Format. Any Scale. Any Stage

Production Capabilities

Any Format. Any Scale. Any Stage

Production Capabilities

Any Format. Any Scale. Any Stage

Production Capabilities

Formats

System

Workflow

QC

Final Deliverables

Fit for purpose

HTP scale
(24-well plate)

Standard formats

ExpiCHOᵀᴹ
Expi293ᵀᴹ

One step affinity:
Protein A
Protein L
IMAC
CH1

µCE-SDS

Certificate of analysis (CoA)

Purified antibodies

Screening (µg scale)

HTP scale
(15 mL)

Standard formats

Complex Formats

ExpiCHOᵀᴹ

Two step purification:
Affinity followed by polishing SE C (tandem system)

µCE-SDS
SEC-HPLC

Intact-MS
(for complex formats)

Certificate of analysis (CoA)

Overview report (PPT)

Purified antibodies

PoC
Format screening
(mg scale)

FLASK scale
(From 500mL to above 200L)

Any format

ExpiCHOᵀᴹ
Expi293ᵀᴹ

Customizable DSP workflows:
multiple affinity and polishing chromatography techniques available

µCE-SDS
SEC-HPLC
Intact-MS
Endotoxin testing

Additional QC available

Certificate of analysis (CoA)

Overview report (PPT)

Purified antibodies

Large scale

GLP certified

Support with reports for IND filling

HTP Scale — 24-well plate | µg scale | Screening  

Best for: large panel screening — µg quantities per clone


  • Formats: standard formats

  • System: ExpiCHO and Expi293

  • Workflow: one-step affinity purification — Protein A, Protein L, IMAC, or CH1

  • QC: µCE-SDS

  • Deliverables: Certificate of Analysis (CoA), purified antibodies

HTP Scale — 24-well plate | µg scale | Screening  

Best for: large panel screening — µg quantities per clone


  • Formats: standard formats

  • System: ExpiCHO and Expi293

  • Workflow: one-step affinity purification — Protein A, Protein L, IMAC, or CH1

  • QC: µCE-SDS

  • Deliverables: Certificate of Analysis (CoA), purified antibodies

HTP Scale — 24-well plate | µg scale | Screening  

Best for: large panel screening — µg quantities per clone


  • Formats: standard formats

  • System: ExpiCHO and Expi293

  • Workflow: one-step affinity purification — Protein A, Protein L, IMAC, or CH1

  • QC: µCE-SDS

  • Deliverables: Certificate of Analysis (CoA), purified antibodies

HTP Scale — 15 mL | mg scale | Proof of Concept & Format Screening  

Best for: PoC and format comparison — mg quantities


  • Formats: standard formats and complex formats

  • System: ExpiCHO

  • Workflow: two-step purification — affinity followed by polishing SEC (tandem system)

  • QC: µCE-SDS, SEC-HPLC, Intact-MS for complex formats

  • Deliverables: CoA, overview report (PPT), purified antibodies

HTP Scale — 15 mL | mg scale | Proof of Concept & Format Screening  

Best for: PoC and format comparison — mg quantities


  • Formats: standard formats and complex formats

  • System: ExpiCHO

  • Workflow: two-step purification — affinity followed by polishing SEC (tandem system)

  • QC: µCE-SDS, SEC-HPLC, Intact-MS for complex formats

  • Deliverables: CoA, overview report (PPT), purified antibodies

HTP Scale — 15 mL | mg scale | Proof of Concept & Format Screening  

Best for: PoC and format comparison — mg quantities


  • Formats: standard formats and complex formats

  • System: ExpiCHO

  • Workflow: two-step purification — affinity followed by polishing SEC (tandem system)

  • QC: µCE-SDS, SEC-HPLC, Intact-MS for complex formats

  • Deliverables: CoA, overview report (PPT), purified antibodies

Flask Scale — 50 mL to >200 L | mg-g scale | Large-scale, GLP, IND support  

Best for: preclinical studies, tox batches, IND-enabling manufacturing


  • Formats: any format

  • System: ExpiCHO and Expi293

  • Workflow: customisable DSP workflows — multiple affinity and polishing chromatography techniques available

  • QC: µCE-SDS, SEC-HPLC, Intact-MS, endotoxin testing, additional QC available

  • Deliverables: CoA, overview report (PPT), purified antibodies

  • GLP certified — support with reports for IND filing

Flask Scale — 50 mL to >200 L | mg-g scale | Large-scale, GLP, IND support  

Best for: preclinical studies, tox batches, IND-enabling manufacturing


  • Formats: any format

  • System: ExpiCHO and Expi293

  • Workflow: customisable DSP workflows — multiple affinity and polishing chromatography techniques available

  • QC: µCE-SDS, SEC-HPLC, Intact-MS, endotoxin testing, additional QC available

  • Deliverables: CoA, overview report (PPT), purified antibodies

  • GLP certified — support with reports for IND filing

Flask Scale — 50 mL to >200 L | mg-g scale | Large-scale, GLP, IND support  

Best for: preclinical studies, tox batches, IND-enabling manufacturing


  • Formats: any format

  • System: ExpiCHO and Expi293

  • Workflow: customisable DSP workflows — multiple affinity and polishing chromatography techniques available

  • QC: µCE-SDS, SEC-HPLC, Intact-MS, endotoxin testing, additional QC available

  • Deliverables: CoA, overview report (PPT), purified antibodies

  • GLP certified — support with reports for IND filing

Format coverage  

More than 75 different antibody formats produced. The in-house backbone library of more than 900 antibodies means the most common formats are available immediately — without de novo vector construction delays.


  • Standard IgG (IgG1, IgG2, IgG4 and engineered Fc variants)

  • Fab, scFv, VHH and VHH-Fc

  • Bispecific formats: Duobody, bYlok, Knob-in-Hole (KIH), FORCE, and others

  • Multispecific formats: >1,500 produced with >90% success rate

  • ADC intermediates and conjugation-ready formats

  • Antigens for immunisation and functional assay use

Format coverage  

More than 75 different antibody formats produced. The in-house backbone library of more than 900 antibodies means the most common formats are available immediately — without de novo vector construction delays.


  • Standard IgG (IgG1, IgG2, IgG4 and engineered Fc variants)

  • Fab, scFv, VHH and VHH-Fc

  • Bispecific formats: Duobody, bYlok, Knob-in-Hole (KIH), FORCE, and others

  • Multispecific formats: >1,500 produced with >90% success rate

  • ADC intermediates and conjugation-ready formats

  • Antigens for immunisation and functional assay use

Format coverage  

More than 75 different antibody formats produced. The in-house backbone library of more than 900 antibodies means the most common formats are available immediately — without de novo vector construction delays.


  • Standard IgG (IgG1, IgG2, IgG4 and engineered Fc variants)

  • Fab, scFv, VHH and VHH-Fc

  • Bispecific formats: Duobody, bYlok, Knob-in-Hole (KIH), FORCE, and others

  • Multispecific formats: >1,500 produced with >90% success rate

  • ADC intermediates and conjugation-ready formats

  • Antigens for immunisation and functional assay use

Antigens That Drive Discovery

Antigen Production

High-quality antigen is the foundation of every successful antibody discovery campaign. AnyFormat Manufacturing has produced more than 500 antigens from more than 65 protein families — with fit-for-purpose literature review and workflow design for every project.

Antigens That Drive Discovery

Antigen Production

High-quality antigen is the foundation of every successful antibody discovery campaign. AnyFormat Manufacturing has produced more than 500 antigens from more than 65 protein families — with fit-for-purpose literature review and workflow design for every project.

Antigens That Drive Discovery

Antigen Production

High-quality antigen is the foundation of every successful antibody discovery campaign. AnyFormat Manufacturing has produced more than 500 antigens from more than 65 protein families — with fit-for-purpose literature review and workflow design for every project.

Antigen production at a glance  

  • More than 500 antigens produced

  • From more than 65 protein families

  • From more than 15 different species

  • Fit-for-purpose literature review and workflow design for every project

  • General yield of the top 10 antigen families: ~90 mg/L

Antigen production at a glance  

  • More than 500 antigens produced

  • From more than 65 protein families

  • From more than 15 different species

  • Fit-for-purpose literature review and workflow design for every project

  • General yield of the top 10 antigen families: ~90 mg/L

Antigen production at a glance  

  • More than 500 antigens produced

  • From more than 65 protein families

  • From more than 15 different species

  • Fit-for-purpose literature review and workflow design for every project

  • General yield of the top 10 antigen families: ~90 mg/L

Top 10 antigen families covered  

  • Immunoglobulin-like proteins

  • Cytokines

  • Protein kinases

  • TNF receptors

  • Fc receptor-like proteins

  • T-cell receptors

  • Adhesion molecules

  • EGF receptors

  • Lectins

  • Integrin beta chains

Top 10 antigen families covered  

  • Immunoglobulin-like proteins

  • Cytokines

  • Protein kinases

  • TNF receptors

  • Fc receptor-like proteins

  • T-cell receptors

  • Adhesion molecules

  • EGF receptors

  • Lectins

  • Integrin beta chains

Top 10 antigen families covered  

  • Immunoglobulin-like proteins

  • Cytokines

  • Protein kinases

  • TNF receptors

  • Fc receptor-like proteins

  • T-cell receptors

  • Adhesion molecules

  • EGF receptors

  • Lectins

  • Integrin beta chains

Expression systems  

  • Mammalian: Expi-CHO and Expi293 — for glycosylated and complex antigens

  • Bacterial: E. coli BL21 (DE3) and E. coli Shuffle — for non-glycosylated and simple antigens

Expression systems  

  • Mammalian: Expi-CHO and Expi293 — for glycosylated and complex antigens

  • Bacterial: E. coli BL21 (DE3) and E. coli Shuffle — for non-glycosylated and simple antigens

Expression systems  

  • Mammalian: Expi-CHO and Expi293 — for glycosylated and complex antigens

  • Bacterial: E. coli BL21 (DE3) and E. coli Shuffle — for non-glycosylated and simple antigens

Quality controls  

  • IPC: SDS-PAGE on the supernatant

  • Standard final QC: SDS-PAGE, SEC-MALS, Intact MS, and endotoxin analysis

  • Additional QC: Western blot or other assays available

Quality controls  

  • IPC: SDS-PAGE on the supernatant

  • Standard final QC: SDS-PAGE, SEC-MALS, Intact MS, and endotoxin analysis

  • Additional QC: Western blot or other assays available

Quality controls  

  • IPC: SDS-PAGE on the supernatant

  • Standard final QC: SDS-PAGE, SEC-MALS, Intact MS, and endotoxin analysis

  • Additional QC: Western blot or other assays available

 Post-processing  

  • Biotinylation — for SPR, BLI, and FACS-based assays

  • Conjugation — for screening and functional assay use

  • Labelling — fluorescent labelling for flow cytometry and cell-based assays

  • Digestion — Fab, F(ab')2 and other fragment generation

 Post-processing  

  • Biotinylation — for SPR, BLI, and FACS-based assays

  • Conjugation — for screening and functional assay use

  • Labelling — fluorescent labelling for flow cytometry and cell-based assays

  • Digestion — Fab, F(ab')2 and other fragment generation

 Post-processing  

  • Biotinylation — for SPR, BLI, and FACS-based assays

  • Conjugation — for screening and functional assay use

  • Labelling — fluorescent labelling for flow cytometry and cell-based assays

  • Digestion — Fab, F(ab')2 and other fragment generation

On Time. On Quality. On Budget

Process & Deliverables  

98% of projects delivered on time. 42% delivered ahead of schedule. AnyFormat Manufacturing is built around programme timelines — not the other way around.

On Time. On Quality. On Budget

Process & Deliverables  

98% of projects delivered on time. 42% delivered ahead of schedule. AnyFormat Manufacturing is built around programme timelines — not the other way around.

On Time. On Quality. On Budget

Process & Deliverables  

98% of projects delivered on time. 42% delivered ahead of schedule. AnyFormat Manufacturing is built around programme timelines — not the other way around.

What You Receive

  • HTP 24-well plate

    • Purified antibodies at µg scale

    • Certificate of Analysis (CoA)

    HTP 15 mL

    • Purified antibodies at mg scale

    • Certificate of Analysis (CoA)

    • Overview report (PPT) with raw and processed data

    Flask scale

    • Purified antibodies at mg–g scale

    • Certificate of Analysis (CoA)

    • Overview report (PPT) with raw and processed data

    • GLP-certified batches available

    • IND filing support reports available

Quality standards

  • µCE-SDS for purity assessment at all scales

  • SEC-HPLC for aggregation and monomer content (15 mL and flask scale)

  • Intact-MS for complex formats — confirming correct assembly

  • Endotoxin testing at flask scale

  • Additional QC available on request

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